Search results for "Cord lining"

showing 4 items of 4 documents

The expression of CD68 in human umbilical cord mesenchymal stem cells: new evidences of presence in non-myeloid cell types.

2009

Since their first identification in bone marrow [2],MSC have attracted much attention for thei r potential todifferentiate towards several mature tissues. The efforts ofthe researchers aimed in finding new tissues, whichshould provide adequate cell numbers for regenerativemedicine applications (and between them, extraembryonicsources as umbilical cord and amniotic membrane, arebeing viewed with extreme interest).

Cell typeSettore BIO/16 - Anatomia UmanaImmunologyMesenchymal stem cellAntigens Differentiation MyelomonocyticMesenchymal Stem CellsGeneral MedicinePlacenta cord bankingBiologyUmbilical cordCord liningUmbilical Cordmedicine.anatomical_structureAntigens CDCell Line TumorCancer researchmedicineHumansMyeloid CellsStem cellCD68 mesenchymal stem cells umbilical cord immune regulation stem cell markersStem cell transplantation for articular cartilage repairAdult stem cellScandinavian journal of immunology
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Isolation and characterization of Oct-4+/HLA-G+ mesenchymal stem cells from human umbilical cord matrix: differentiation potential and detection of n…

2008

The presence of multipotent cells in several adult and embryo-related tissues opened new paths for their use in regenerative medicine. Extraembryonic tissues such as umbilical cord are considered a promising source of stem cells, potentially useful in therapy. The characterization of cells from the umbilical cord matrix (Wharton''s Jelly) and amniotic membrane revealed the presence of a population of mesenchymal-like cells, sharing a set of core-markers expressed by "mesenchymal stem cells". Several reports enlightened the differentiation capabilities of these cells, even if at times the lack of an extensive characterization of surface markers and immune co-stimulators expression revealed h…

HistologyCell Culture TechniquesClinical uses of mesenchymal stem cellsCell SeparationBiologyUmbilical CordHLA AntigensHumansAmnionMolecular BiologyCell ProliferationStem cell transplantation for articular cartilage repairHLA-G AntigensSettore BIO/16 - Anatomia UmanaMultipotent Stem CellsHistocompatibility Antigens Class IMesenchymal stem cellCell DifferentiationMesenchymal Stem CellsAmniotic stem cellsCell BiologyTelomereCord liningCell biologyMedical Laboratory TechnologyMesenchymal stem cells Umbilical cord matrix Differentiation protocols Tolerogenic properties Self-renewal markersAmniotic epithelial cellsImmunologyStem cellOctamer Transcription Factor-3BiomarkersAdult stem cellHistochemistry and Cell Biology
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Immunohistochemical and transcriptional expression of matrix metalloproteinases in full-term human umbilical cord and Human Umbilical Vein Endothelia…

2010

Matrix metalloproteinases (MMPs) are extracellular zinc-dependent endopeptidases involved in the degradation and remodelling of extracellular matrix in physiological and pathological processes. MMPs also have a role on cell proliferation, migration, differentiation, angiogenesis and apoptosis. Umbilical cord is a special organ subjected to many changes during pre-natal life and whose cells can maintain a certain degree of plasticity also in post-natal period; for example recently they have been used as a source of stem cells. In this work we investigated the expression of MMPs in human umbilical cord and Human Umbilical Vein Endothelial Cells (HUVEC) though immunohistochemistry, RT-PCR and …

Settore BIO/17 - IstologiaUmbilical VeinsHistologyPhysiologyAngiogenesisBiologyMatrix metalloproteinaseUmbilical cordGene Expression Regulation EnzymologicUmbilical veinUmbilical CordExtracellular matrixMatrix Metalloproteinase 10Matrix Metalloproteinase 13ExtracellularmedicineHumansCells CulturedReverse Transcriptase Polymerase Chain ReactionEndothelial CellsCell BiologyGeneral MedicineMatrix metalloproteinases human umbilical cord HUVEC.ImmunohistochemistryMatrix MetalloproteinasesCord liningCell biologyMatrix Metalloproteinase 8medicine.anatomical_structureMatrix Metalloproteinase 9ImmunologyMatrix Metalloproteinase 2Matrix Metalloproteinase 3Stem cellJournal of Molecular Histology
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Energy Metabolism Analysis of Three Different Mesenchymal Stem Cell Populations of Umbilical Cord Under Normal and Pathologic Conditions

2020

AbstractHuman umbilical cord mesenchymal stem cells (hUC-MSCs) are a pivotal source of therapeutically active cells for regenerative medicine due to their multipotent differentiation potential, immunomodulatory and anti-inflammatory proprieties, as well as logistical collection advantages without ethical concerns. However, it remains poorly understood whether MSCs from different compartments of the human umbilical cord are therapeutically superior than others. In this study, MSCs were isolated from Wharton’s jelly (WJ-MSCs), perivascular region (PV-MSCs) and cord lining (CL-MSCs) of hUC. These cells expressed the mesenchymal markers (CD90, CD73), stemness marker (OCT4), endothelial cell adh…

Wharton’s JellyCell Survivalmedicine.medical_treatmentBioenergeticIschemic diseaseBiologyBioenergeticsUmbilical cordArticleUmbilical CordIschemic diseasesWharton's jellymedicineHumansUmbilical cord mesenchymal stem cellWharton JellyPerivascularCell ShapeStem cell therapyUmbilical cord mesenchymal stem cellsMesenchymal stem cellMesenchymal Stem CellsStem-cell therapyCord liningCell biologyMitochondriaEndothelial stem cellStrokemedicine.anatomical_structureCD146Stem cellEnergy MetabolismBiomarkers
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